Transdermal absorption offers a non-invasive pathway to deliver nutrients and compounds directly into the body. At Dermisorb, we study how this route can be used to support individuals with digestive impairments—bypassing the limitations of oral delivery. Our research is focused on understanding what’s possible and how it might change access to essential compounds in the future.
ExploreThe skin is naturally resistant to charged substances—its structure and chemistry evolved to repel water, ions, and pathogens. But with the right tools, even charged electrolytes like sodium can pass through. Our research explores how chemical and electrical methods can modulate the skin’s barrier properties and enable transdermal delivery once thought impossible.
ExploreMost orally ingested compounds pass through the liver before reaching systemic circulation—a process known as first-pass metabolism. This is often essential: it protects the body from toxins, controls absorption rate, and transforms compounds into their active or inactive forms. But it also creates challenges. In some cases, the liver rapidly breaks down beneficial compounds before they can act, leading to poor bioavailability.
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